The Drosophila Anion Exchanger (DAE) lacks a detectable interaction with the spectrin cytoskeleton
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چکیده
منابع مشابه
The spectrin-associated cytoskeleton in mammalian heart.
The membrane-associated cytoskeleton of the cardiac muscle cell is emerging as an important element in the maintenance of normal cell functioning. Recently it was shown that when proteins (betaII-spectrin, muscle Lim-only protein, ankyrin-B, ankyrin-G) of this system are defective or deficient, cardiac malfunction ensues. It is well-established that the spectrin cytoskeleton is associated with ...
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ARTICLE HISTORY Received 19 July 2017 Revised 12 September 2017 Accepted 13 September 2017 ABSTRACT Bin-Amphiphysin-Rvs (BAR) domain containing proteins with their membrane deforming properties have emerged as key players in shaping up neuronal morphology and regulating cytoskeletal dynamics. However, the in vivo contexts in which BAR-domain proteins integrate membrane dynamics with cytoskeleta...
متن کاملProtein 4.2 interaction with hereditary spherocytosis mutants of the cytoplasmic domain of human anion exchanger 1.
AE1 (anion exchanger 1) and protein 4.2 associate in a protein complex bridging the erythrocyte membrane and cytoskeleton; disruption of the complex results in unstable erythrocytes and HS (hereditary spherocytosis). Three HS mutations (E40K, G130R and P327R) in cdAE1 (the cytoplasmic domain of AE1) occur with deficiencies of protein 4.2. The interaction of wild-type AE1, AE1HS mutants, mdEA1 (...
متن کاملNovel role for the Lu/BCAM-spectrin interaction in actin cytoskeleton reorganization.
Lu/BCAM (Lutheran/basal cell-adhesion molecule) is a laminin 511/521 receptor expressed in erythroid and endothelial cells, and in epithelial tissues. The RK573-574 (Arg573-Lys574) motif of the Lu/BCAM cytoplasmic domain interacts with αI-spectrin, the main component of the membrane skeleton in red blood cells. In the present paper we report that Lu/BCAM binds to the non-erythroid αII-spectrin ...
متن کاملUranium Ions Removal Using Amberlite CG-400 Anion Exchanger Resin in the Presence of Sulfate Anions
Uptake of uranium (VI) ions using an anion exchanger resin, namely amberlite CG-400, was studied through this work in the presence of sulfate anions. Impact of various parameters including pH, contact time, initial concentration of uranium ions and intrusion with different anion contents (phosphate, chloride,sulfate, nitrate and fluoride) was examined on the sorption performance of the resin. A...
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ژورنال
عنوان ژورنال: Journal of Negative Results in BioMedicine
سال: 2010
ISSN: 1477-5751
DOI: 10.1186/1477-5751-9-5